Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length441 amino acids

Chemical FormulaC2235H3580N618O618S24

DescriptionStandard

        MVTILLSATLNPGVQVKLTQKGLDYARQVGMEKLKQKLQTIQIPNFSGKRRVKYSLTNVRIVAMGIPNSALTLAPGTGVRMSIRDAFINVRGNWRVRYKFIRTSGSFDLNVSGLTIGTTISVTSGAGGRPVVSSVNCRASIGRTRIKFHGRASWLYNIFRKLIERPMRKKMEEQVRENNVSLMLEYMLINFHCAAVLARVDKHAEIEYSMVSSPVVTQSSIALNLKGQFYNIGRHQEPPFSPQPFSMPTQQHMVYMGMSAFTANSAGFVYNRAGILSVSITDDMIPSVSPIRLSTSSFGVIIPEISRRFPGLKMILTLSAARDPMVIFKRNNMTIVAVATVTAFAIQPNSTLSPLFVLKLVSYTDLSNKVRKTVKRSFDGDFKNTSQRIFTFCMLQYATLSETQQVIYNTWNNILVKHILMQYMYILHQYIVMYFNIWNNT
    

Molecular Weight49765.66 Da

Isoelectric Point (pI)10.36

Net Charge (pH 7.0)31.08

Net Charge (pH 7.4) 30.39

Charge Density (pH 7.0) 0.0705

GRAVY Index0.02

Hydrophobic Moment 0.83

Boman Index0.07

Instability Index46.31

Aliphatic Index 93.45

Aromaticity 0.0952

Extinction Coeff. Reduced 45840.00

Extinction Coeff. Oxidized 45965.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0151569 VERIFIED: NO

Provenance & Taxonomy

OrganismMyripristis murdjan [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria