Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC930H1418N208O286S7

DescriptionStandard

        QIDDLAEVDYSLSSSPAVFQPFIDLDLKGVFFPAGNYTDSPYVAASLTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFTMTIAEETCSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMSTEIPIISLQKDSFTVQIQGSVEVLAVLPDSTIQSLFTLNIVANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight20312.88 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-13.24

Net Charge (pH 7.4) -13.52

Charge Density (pH 7.0) -0.0720

GRAVY Index0.34

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index48.22

Aliphatic Index 98.04

Aromaticity 0.1304

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7841.67

LogP -86.85

H-bond Donors 267.0

H-bond Acceptors 280.0

Rotatable Bonds 650.0

Heavy Atoms 1431.0

Ring Count 34.0

Amide Bonds 199.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344243 VERIFIED: NO

Provenance & Taxonomy

OrganismCopsychus sechellarum [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria