Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC553H885N151O167S3

DescriptionStandard

        PDLTGYEKFGLGNVNYNISRIRVTAVEFPNASISLIPRTGIKLVIGNASLTINMNWNIRTWMFKDSGRSTAYISKVFVTAIFSTPLDSTGHASISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12417.05 Da

Isoelectric Point (pI)9.73

Net Charge (pH 7.0)5.04

Net Charge (pH 7.4) 4.90

Charge Density (pH 7.0) 0.0442

GRAVY Index0.00

Hydrophobic Moment 0.58

Boman Index0.09

Instability Index15.98

Aliphatic Index 92.37

Aromaticity 0.0877

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5134.62

LogP -58.46

H-bond Donors 185.0

H-bond Acceptors 176.0

Rotatable Bonds 409.0

Heavy Atoms 874.0

Ring Count 17.0

Amide Bonds 122.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0237654 VERIFIED: NO

Provenance & Taxonomy

OrganismPenelope pileata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria