Peptide Database

Peptide NameSLAY-screened peptide P211

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC107H157N29O35

DescriptionStandard

        LFHSEFSDTQRSIHNISDYL
    

Molecular Weight2409.56 Da

Isoelectric Point (pI)5.21

Net Charge (pH 7.0)-2.06

Net Charge (pH 7.4) -2.37

Charge Density (pH 7.0) -0.1031

GRAVY Index-0.57

Hydrophobic Moment 0.68

Boman Index-0.04

Instability Index69.80

Aliphatic Index 78.00

Aromaticity 0.1500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1054.94

LogP -11.27

H-bond Donors 37.0

H-bond Acceptors 35.0

Rotatable Bonds 78.0

Heavy Atoms 171.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0178521 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/