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MYP_044241
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Basic Information
NP-06
Antimicrobial
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antimicrobial ▸ Quorum sensing modulation
Antiviral
Antiviral ▸ Anti-HIV
Enzyme modulation ▸ Enzyme inhibition ▸ Protein kinase inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Regulatory peptide ▸ Cell-cell communication
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
21 amino acids
C97H137N23O27S4
Standard
Sequence
CLGVGSCNDFAGCGYAIVCFW
Physicochemical Analysis
2185.52 Da
4.05
-1.28
-1.54
-0.0609
1.16
0.30
0.50
29.78
74.29
0.1905
6990.00
7240.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
781.96
-6.72
31.0
30.0
64.0
151.0
5.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017820 VERIFIED: YES
Provenance & Taxonomy
Streptomyces strain AA6532 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV 2ROD
6.0 μM
IC50
PMID8619594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8619594/
RECORD: Rec_0053897 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
1-13, 7-19
lactam linkage between C1 and D9, disulfide bond between C1 and C13, disulfide bond between C7 and C19
Bio-Activity Profile
Cell-Cell Communication Quorum Sensing
PaperQuorumpeps database: chemical space, microbial origin and functionality of quorum sensing peptides PMID23180797 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23180797/
RECORD: Rec_0068257 VERIFIED: YES
Provenance & Taxonomy
Streptomyces sp. No. [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Anti-HIV Antimicrobial
PaperPubMed PMID: 8619594 PMID8619594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8619594/
RECORD: Rec_0069022 VERIFIED: YES
Provenance & Taxonomy
Streptomyces sp [Bacterium]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Protein kinase inhibitor Enzyme Inhibitor Non-hemolytic
No Target Organism Found
PMID8689231;8689232 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8689231/
RECORD: Rec_0164470 VERIFIED: YES
Provenance & Taxonomy
Streptomyces strain AA6532 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1ERS104pre
1.3 μM
IC50
PMID8619594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8619594/
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