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MYP_044214
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Basic Information
Parigidin-br1
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
32 amino acids
C140H219N35O45S6
Standard
Sequence
GGSVPCGESCVFIPCITSLAGCSCKNKVCYYD
Physicochemical Analysis
3304.83 Da
6.15
-0.30
-0.60
-0.0093
0.48
0.32
0.22
51.63
66.88
0.0938
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1259.18
-15.37
49.0
51.0
102.0
226.0
5.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014755 VERIFIED: YES
Provenance & Taxonomy
Palicourea rigida [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial Insecticidal Anti-Gram-negative
Escherichia coli
PMID22074926 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22074926/
RECORD: Rec_0026766 VERIFIED: YES
Provenance & Taxonomy
Palicourea rigida [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic cyclotide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Insecticidal
PaperIdentification and Structural Characterization of Novel Cyclotide with Activity against an Insect Pest of Sugar Cane
RECORD: Rec_0055182 VERIFIED: YES
Provenance & Taxonomy
Palicourea rigida [Plant]
Structure & Mods
stapled cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
No specific N-terminal
No specific C-terminal
6-22; 10-24; 15-29
Bio-Activity Profile
Toxin Hemolytic
PMID22074926 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22074926/
RECORD: Rec_0070023 VERIFIED: YES
Provenance & Taxonomy
Palicourea rigida [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial Insecticidal
Spodoptera frugiperda
1.7 μM
EC50
PMID22074926 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22074926/
RECORD: Rec_0116754 VERIFIED: YES
Provenance & Taxonomy
Palicourea rigida [Plant]
Structure & Mods
stapled cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
No specific N-terminal
No specific C-terminal
6-22; 10-24; 15-29
Bio-Activity Profile
Toxin Cytotoxic
PMID22074926 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22074926/
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