Peptide Database

Peptide NameChimeric CNP-F

Function Ontology

Natriuretic

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC250H433N81O68S3

DescriptionStandard

        RPQLKAPPKKSEKRQQVCFGLKLDRIGSMSGLGCVQQRKESKKPPAKLQPR
    

Molecular Weight5757.81 Da

Isoelectric Point (pI)10.79

Net Charge (pH 7.0)10.74

Net Charge (pH 7.4) 10.49

Charge Density (pH 7.0) 0.2105

GRAVY Index-1.14

Hydrophobic Moment 0.45

Boman Index-0.38

Instability Index62.47

Aliphatic Index 61.18

Aromaticity 0.0196

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2460.62

LogP -27.07

H-bond Donors 85.0

H-bond Acceptors 82.0

Rotatable Bonds 202.0

Heavy Atoms 402.0

Ring Count 7.0

Amide Bonds 56.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0423226 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyNatriuretic peptide

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide18-34

Bio-Activity Profile

Function

Natriuretic

MethodCompetitive Radioimmunoassay

Half-LifeRat plasma (Intravenous), in vivo; 1042.8 s