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MYP_044170
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Basic Information
H2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Standard
14 amino acids
C69H109N23O18
Standard
Sequence
ASHLGHHALDHLLK
Physicochemical Analysis
1548.75 Da
7.14
0.14
-0.25
0.0103
-0.19
0.50
0.13
3.22
125.71
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
639.89
-4.98
22.0
22.0
50.0
110.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0321384 VERIFIED: YES
Provenance & Taxonomy
Holothuria tubulosa [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Listeria monocytogenes ATCC 19114 [Mueller –Hinton Broth (MHB) medium]
5000 μg/mL
MIC
PMID30857142 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30857142/
RECORD: Rec_0332268 VERIFIED: YES
Provenance & Taxonomy
Holothuria tubulosa [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 29213, Staphylococcus aureus ATCC 25923, Staphylococcus aureus ATCC 6538, Staphylococcus epidermidis ATCC 35984, Enterococcus faecalis ATCC 29212, and Pseudomonas aeruginosa ATCC 15442
12500 μg/mL
MIC
PaperImmune mediators of sea-cucumber Holothuria tubulosa (Echinodermata) as source of novel antimicrobial and anti-staphylococcal biofilm agents
RECORD: Rec_0390240 VERIFIED: YES
Provenance & Taxonomy
Holothuria tubulosa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-positive
Staphylococcus aureus
125 μg/mL
MIC
RECORD: Rec_0399841 VERIFIED: YES
Provenance & Taxonomy
Holothuria tubulosa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antibacterial
Staphylococcus aureus ATCC 25923
2.067, 0.969 μM
Safranin staining
RECORD: Rec_0426298 VERIFIED: YES
Provenance & Taxonomy
Holothuria tubulosa [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Listeria monocytogenes 103 [Mueller –Hinton Broth (MHB) medium]
5000 μg/mL
MIC
PMID30857142 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30857142/
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