Peptide Database

Peptide NamePhenoloxidase-activating factor 2 (45 KDa PPAF) (Hd-45) (Prophenoloxidase-activating factor II) (Serine protease-like PPAF-2) [Cleaved into: Phenoloxidase-activating factor 2 light chain; Phenoloxidase-activating factor 2 heavy chain]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length415 amino acids

Chemical FormulaC2004H3146N546O606S21

DescriptionStandard

        MKRLFVITAFFLFGAEAQNSVIDAAVVNIFGNASEYIPPGYEIVTKAPLGALTALPRCGTGADQGKKVCIVYHRCDGVTNTVTPEEVINTTGEGIFDIRENANECESYLDVCCGLPEGGVLPTPSPTPPVVPVLKPSFCGIRNERGLDFKITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQQSQIFDSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLKFVLDQTFVCAGGEQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIGCGDENVPGVYANVAHFRNWIDQEMQAKGLSTTPYVE
    

Molecular Weight45257.08 Da

Isoelectric Point (pI)5.27

Net Charge (pH 7.0)-9.15

Net Charge (pH 7.4) -9.96

Charge Density (pH 7.0) -0.0220

GRAVY Index-0.15

Hydrophobic Moment 0.61

Boman Index0.06

Instability Index31.28

Aliphatic Index 84.53

Aromaticity 0.0795

Extinction Coeff. Reduced 43890.00

Extinction Coeff. Oxidized 44890.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0310666 VERIFIED: YES

Provenance & Taxonomy

OrganismHolotrichia diomphalia [Animal]

FamilyPeptidase S1; CLIP subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic

TargetNo Target Organism Found