Peptide Database

Peptide NameHyen E

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC137H213N37O43S6

DescriptionStandard

        GVPCGESCVYIPCFTGIINCSCRDKVCYNN
    

Molecular Weight3258.77 Da

Isoelectric Point (pI)6.03

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.60

Charge Density (pH 7.0) -0.0099

GRAVY Index0.29

Hydrophobic Moment 0.49

Boman Index0.14

Instability Index18.43

Aliphatic Index 68.00

Aromaticity 0.1000

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1282.58

LogP -15.09

H-bond Donors 49.0

H-bond Acceptors 49.0

Rotatable Bonds 100.0

Heavy Atoms 223.0

Ring Count 5.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0406841 VERIFIED: YES

Provenance & Taxonomy

Organismmedicinal herb Hybanthus enneaspermus [Plant]

Structure & Mods

Configcyclic/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

TargetHuman red blood cells (hRBCs)

Activity50 μM

MethodHC50

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