Peptide Database

Peptide NameAngiotensin I-converting enzyme inhibitory peptide 8

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC70H118N26O26S

DescriptionStandard

        CRQNTLGHNTQTSIAQ
    

Molecular Weight1771.91 Da

Isoelectric Point (pI)8.26

Net Charge (pH 7.0)0.84

Net Charge (pH 7.4) 0.57

Charge Density (pH 7.0) 0.0523

GRAVY Index-0.99

Hydrophobic Moment 0.29

Boman Index-0.22

Instability Index20.89

Aliphatic Index 55.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 886.77

LogP -14.75

H-bond Donors 31.0

H-bond Acceptors 29.0

Rotatable Bonds 59.0

Heavy Atoms 123.0

Ring Count 1.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050866 VERIFIED: YES

Provenance & Taxonomy

OrganismStichopus horrens [Animal]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity80±0 μM

MethodIC50

RECORD: Rec_0417288 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme (ACE)

Activity80.0