Peptide Database

Peptide NameCycloviolacin H4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC129H209N35O38S6

DescriptionStandard

        GIPCGESCVWIPCLTSAVGCSCKSKVCYR
    

Molecular Weight3050.64 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0586

GRAVY Index0.55

Hydrophobic Moment 0.30

Boman Index0.18

Instability Index18.42

Aliphatic Index 73.79

Aromaticity 0.0690

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1148.95

LogP -13.01

H-bond Donors 47.0

H-bond Acceptors 46.0

Rotatable Bonds 94.0

Heavy Atoms 208.0

Ring Count 5.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0043793 VERIFIED: YES

Provenance & Taxonomy

OrganismViola biflora [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)