Peptide Database

Peptide NameSLAY-screened peptide P19

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC77H132N24O25S

DescriptionStandard

        PCATALIPSPRQDSRTL
    

Molecular Weight1826.08 Da

Isoelectric Point (pI)8.68

Net Charge (pH 7.0)0.95

Net Charge (pH 7.4) 0.88

Charge Density (pH 7.0) 0.0559

GRAVY Index-0.33

Hydrophobic Moment 0.44

Boman Index-0.11

Instability Index81.34

Aliphatic Index 80.59

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 782.46

LogP -10.29

H-bond Donors 29.0

H-bond Acceptors 27.0

Rotatable Bonds 55.0

Heavy Atoms 127.0

Ring Count 3.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409517 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/