Peptide Database

Peptide NameHill-Knot 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC139H240N42O40S7

DescriptionStandard

        IKCVPSQCNQICRVLGKKCGYCKNASTCVCL
    

Molecular Weight3364.10 Da

Isoelectric Point (pI)9.01

Net Charge (pH 7.0)4.69

Net Charge (pH 7.4) 4.37

Charge Density (pH 7.0) 0.1512

GRAVY Index0.27

Hydrophobic Moment 0.64

Boman Index-0.00

Instability Index16.58

Aliphatic Index 81.61

Aromaticity 0.0323

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1346.79

LogP -16.23

H-bond Donors 53.0

H-bond Acceptors 52.0

Rotatable Bonds 113.0

Heavy Atoms 228.0

Ring Count 2.0

Amide Bonds 34.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0413568 VERIFIED: YES

Provenance & Taxonomy

OrganismHermetia illucens [Animal]

FamilyDefensin

Tax ID343691

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetMRC-5 SV2

Activity3.76 μM

MethodIC50

FIRST PREV 1 2

Showing 1 records on this page Ã‚Â· Page 2 of 2