Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC155H236N42O53S7

DescriptionStandard

        DQFVCADKGGTCNYSPCPSYSKMEGTCYNGKAKCC
    

Molecular Weight3760.24 Da

Isoelectric Point (pI)7.75

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.39

Charge Density (pH 7.0) 0.0200

GRAVY Index-0.62

Hydrophobic Moment 0.27

Boman Index-0.08

Instability Index22.96

Aliphatic Index 14.00

Aromaticity 0.1143

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1542.23

LogP -21.38

H-bond Donors 58.0

H-bond Acceptors 61.0

Rotatable Bonds 120.0

Heavy Atoms 257.0

Ring Count 6.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0129484 VERIFIED: YES

Provenance & Taxonomy

OrganismElephantulus edwardii [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)