Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length402 amino acids

Chemical FormulaC2003H3178N506O575S17

DescriptionStandard

        MFLWWVLVLVNLVSVATGTNAGVKVRLTQKGLEYAETQHLTIKVPDISGTEKVDLNFPDVPVRMQIVNLGLPKSALGLVPDTGVMLSIGNAYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTIAVTSDDTSRATVSMTNCAATVNVKFHGGKHLIFCPFISCFHDSWLHTVSHSIYLLFQICPLVADSIADINPHLKTLNVLAKVDQYAEIEYSMVGSPVVSNTSIDLGLKVTFSITEPPFSPTPFSLPSQDTDMAGALRLYITDDMIPSGSPICLNTKTFGTFIPQADSKMIYFRLRKSVVTAYTIQPNSTLFPLFVLNLEGSVSTHIYVTELKMAGNVTLNKIDMSLAKSYVGPFQVVVIPKVNARLQEGYPLPAIGKMQLVNSQLQVLKGNLMQYT
    

Molecular Weight44092.81 Da

Isoelectric Point (pI)7.66

Net Charge (pH 7.0)1.25

Net Charge (pH 7.4) 0.43

Charge Density (pH 7.0) 0.0031

GRAVY Index0.26

Hydrophobic Moment 0.64

Boman Index0.19

Instability Index30.02

Aliphatic Index 105.87

Aromaticity 0.0846

Extinction Coeff. Reduced 41370.00

Extinction Coeff. Oxidized 41620.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0040921 VERIFIED: NO

Provenance & Taxonomy

OrganismSinocyclocheilus rhinocerous [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria