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MYP_043967
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Basic Information
TPA (Tritrpticin peptide derivative)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C92H128N28O14
Standard
Sequence
VRRFAWWWAFLRR
Physicochemical Analysis
1850.18 Da
12.00
3.73
3.52
0.2872
-0.27
0.45
-0.15
100.61
67.69
0.3846
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
707.49
-0.33
29.0
18.0
54.0
134.0
8.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0155917 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus subtilis
16 μg/mL
MIC
PMID12207877 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12207877/
RECORD: Rec_0170194 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
60 μg/mL
EC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/16997878/ PMID16997878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16997878/
RECORD: Rec_0176089 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
32 μg/mL
MIC
PMID12207877 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12207877/
RECORD: Rec_0188154 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
S. typhimurim
32 μg/mL
MIC
PMID12207877 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12207877/
RECORD: Rec_0218417 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus
32 μg/mL
MIC
PMID12207877 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12207877/
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