Peptide Database

Peptide NameCecropin A

Function Ontology

—

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC186H318N56O46

DescriptionStandard

        RWKVFKKIEKVGRNIRDGVIKAGPAIEVLGQAKAIGK
    

Molecular Weight4074.86 Da

Isoelectric Point (pI)10.71

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.54

Charge Density (pH 7.0) 0.1827

GRAVY Index-0.26

Hydrophobic Moment 0.91

Boman Index-0.08

Instability Index51.55

Aliphatic Index 105.41

Aromaticity 0.0541

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1683.84

LogP -12.50

H-bond Donors 59.0

H-bond Acceptors 53.0

Rotatable Bonds 145.0

Heavy Atoms 288.0

Ring Count 4.0

Amide Bonds 38.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0097118 VERIFIED: YES

Provenance & Taxonomy

OrganismHelicoverpa armigera [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)