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MYP_043927
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Basic Information
hCGRP(Human Calcitonin gene-related peptide)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Vasoactive neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
37 amino acids
C163H268N50O50S2
Standard
Sequence
ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF
Physicochemical Analysis
3792.31 Da
9.50
2.86
2.59
0.0774
0.21
0.59
0.10
32.84
81.62
0.0541
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1614.83
-21.92
59.0
56.0
122.0
265.0
4.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0158959 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Calcitonin gene-related peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
2-7
Bio-Activity Profile
Hormone Vasodilator
PaperFluorescent Analogues of Human α-Calcitonin Gene-Related Peptide with Potent Vasodilator Activity PMID32079247 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32079247/
RECORD: Rec_0163059 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0222727 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID24449502 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24449502/
RECORD: Rec_0230176 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Pseudomonas aeruginosa ATCC 27853
5.9 μg/mL
MIC
PaperAntimicrobial activity of neuropeptides against a range of micro-organisms from skin, oral, respiratory and gastrointestinal tract sites.
RECORD: Rec_0237060 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PMID18603306 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18603306/
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