Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC426H676N118O128S15

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAVPLNGVQELEEAGSNDTPVAAHQEMSMESWMMPSRVREKRQSHISMCYYCCNCCRANKGCGYCCKF
    

Molecular Weight9979.61 Da

Isoelectric Point (pI)6.68

Net Charge (pH 7.0)-0.40

Net Charge (pH 7.4) -0.87

Charge Density (pH 7.0) -0.0045

GRAVY Index0.14

Hydrophobic Moment 0.47

Boman Index0.08

Instability Index59.08

Aliphatic Index 71.56

Aromaticity 0.0778

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3934.93

LogP -41.02

H-bond Donors 145.0

H-bond Acceptors 145.0

Rotatable Bonds 329.0

Heavy Atoms 687.0

Ring Count 13.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0373499 VERIFIED: NO

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal