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MYP_043856
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Basic Information
Human TC-2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
83 amino acids
C392H665N113O124S5
Standard
Sequence
NLAKGKEESLDSDLYAELRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDES
Physicochemical Analysis
9105.48 Da
8.41
1.91
1.51
0.0230
-0.45
0.60
-0.10
29.31
95.18
0.0120
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3860.87
-40.57
135.0
133.0
321.0
634.0
6.0
88.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0056500 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Cryptococcus neoformans
30 μM
MFC
PMID10877842 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10877842/
RECORD: Rec_0075677 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida glabrata
30 μM
MFC
PMID10877842 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10877842/
RECORD: Rec_0097225 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 42D
PMID10877842 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10877842/
RECORD: Rec_0117167 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID22083479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22083479/
RECORD: Rec_0121463 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus subtilis ATCC6633
0.7 μM
MBC
PaperPubMed PMID: 10877842 | PubMed PMID: 8034022 PMID10877842;8034022 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10877842/
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