Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC417H675N103O108S2

DescriptionStandard

        MKSMVFIVLPLFGFLNLHVFSIVNLTTTLGINTYAAKRVIDIVSTAGTVYAVVGIVAAVVGGGGIGVAILASAKALAQKYGKAAAAAW
    

Molecular Weight8923.57 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)4.58

Net Charge (pH 7.4) 4.30

Charge Density (pH 7.0) 0.0521

GRAVY Index1.16

Hydrophobic Moment 0.64

Boman Index0.46

Instability Index14.16

Aliphatic Index 131.93

Aromaticity 0.0909

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3295.35

LogP -24.48

H-bond Donors 116.0

H-bond Acceptors 116.0

Rotatable Bonds 288.0

Heavy Atoms 630.0

Ring Count 11.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416507 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus danieliae [Bacterium]

FamilyBacteriocin

Tax ID747656

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal