Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC465H754N138O134S8

DescriptionStandard

        MKFLLLVLAALRFLTQVIPASGGGSKCVSDTQGYCRTYCHRGETALFMCNASRKCCASYSFLPKPDLPQLIGNQWQSKRRNTQRKDKKQQTTVTS
    

Molecular Weight10678.33 Da

Isoelectric Point (pI)9.87

Net Charge (pH 7.0)10.52

Net Charge (pH 7.4) 10.15

Charge Density (pH 7.0) 0.1108

GRAVY Index-0.41

Hydrophobic Moment 0.59

Boman Index-0.11

Instability Index33.60

Aliphatic Index 67.79

Aromaticity 0.0842

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4457.05

LogP -51.43

H-bond Donors 163.0

H-bond Acceptors 154.0

Rotatable Bonds 358.0

Heavy Atoms 745.0

Ring Count 14.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0345339 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Animal]

FamilyDefensin

Tax ID61853

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence