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MYP_043649
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Basic Information
Gramicidin S analog 10
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
PXVXXXFPXXXXXF
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0016202 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,5,6,9,10,11,12,13
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis ATCC 12228
4.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0028048 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,5,6,9,10,11,12,13
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
16.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0096542 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,5,6,9,10,11,12,13
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 1110301981HT034-PVL+
16.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0115291 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,5,6,9,10,11,12,13
Bio-Activity Profile
Hemolytic
human red blood cells
100 % hemolysis at 15.6 μM
Hemolysis
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0154719 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,4,5,6,9,10,11,12,13
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
16.0 μg/mL
MIC
PMID20951594 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
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