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MYP_043615
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Basic Information
Esculentin-2-ALb (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
37 amino acids
C172H288N50O47S2
Standard
Sequence
GIFSLIKTAAKFVGKNLLKQAGKAGVEHLACKANNQC
Physicochemical Analysis
3872.56 Da
9.79
4.82
4.53
0.1304
0.09
0.64
0.09
8.11
95.14
0.0541
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1588.93
-16.44
55.0
55.0
136.0
271.0
3.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0213564 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Esculentin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
31-37
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
12.5 μg/mL
MIC
PaperFive novel antimicrobial peptides from skin secretions of the frog, Amolops loloensis. Comp Biochem Physiol B Biochem Mol Biol. 2010 Jan;155(1):72-76. doi: 10.1016/j.cbpb.2009.10.003. PMID: 19843479. PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0248469 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Esculentin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
2.5 μg/mL
MIC
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0259713 VERIFIED: NO
Provenance & Taxonomy
Amolops loloensis [Animal]
Esculentin
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
31-37
Bio-Activity Profile
Antimicrobial
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0259854 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Esculentin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
12.50 μg/mL
MIC
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0275653 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Esculentin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus cereus
7.50 μg/mL
MIC
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
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