‹ ›
MYP_043610
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
18 amino acids
C81H127N23O27S3
Standard
Sequence
TEWTACSKSCGMGFSTRV
Physicochemical Analysis
1951.21 Da
7.74
0.38
0.16
0.0211
-0.13
0.23
0.02
45.97
21.67
0.1111
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
820.41
-11.47
33.0
31.0
62.0
134.0
3.0
17.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0323956 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
CCN family TSR peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic
HUVEC
Endothelial migration assay
PaperPeptides derived from type I thrombospondin repeat-containing proteins of the CCN family inhibit proliferation and migration of endothelial cells PMID17707681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17707681/
RECORD: Rec_0354927 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
CCN family TSR peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic
Endothelial screening context
PaperSupporting Information for Karagiannis and Popel, PNAS (10.1073/pnas.0803241105) PMID18780781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18780781/
RECORD: Rec_0367907 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperA systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13775-13780. doi: 10.1073/pnas.0803241105. PMID: 18780781. PMID18780781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18780781/
FIRST PREV 1 2
Showing 3 records on this page · Page 2 of 2