Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC172H279N49O56S2

DescriptionStandard

        KCNTATCVTQRLADFLIRSSNTIGTVYVPTNVGANTY
    

Molecular Weight3993.48 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0470

GRAVY Index0.03

Hydrophobic Moment 0.68

Boman Index0.06

Instability Index1.45

Aliphatic Index 81.62

Aromaticity 0.0811

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1727.23

LogP -22.97

H-bond Donors 63.0

H-bond Acceptors 60.0

Rotatable Bonds 126.0

Heavy Atoms 279.0

Ring Count 4.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0306403 VERIFIED: YES

Provenance & Taxonomy

OrganismSinocyclocheilus rhinocerous [Animal]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)