Peptide Database

Peptide NamePreprobrevinin-2Ka

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC357H590N94O107S5

DescriptionStandard

        MFTSKKSMLLLFFLGTISLSLCQEEERGADDDEVIEEEVKRGLLSVFKGVLKTAGKHVAGSLLHQLKCKISGGC
    

Molecular Weight8071.39 Da

Isoelectric Point (pI)6.71

Net Charge (pH 7.0)-0.34

Net Charge (pH 7.4) -0.73

Charge Density (pH 7.0) -0.0046

GRAVY Index0.11

Hydrophobic Moment 0.65

Boman Index0.08

Instability Index27.19

Aliphatic Index 102.70

Aromaticity 0.0541

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3238.42

LogP -29.28

H-bond Donors 116.0

H-bond Acceptors 114.0

Rotatable Bonds 286.0

Heavy Atoms 563.0

Ring Count 6.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0063238 VERIFIED: NO

Provenance & Taxonomy

OrganismRana kukunoris [Animal]

FamilyBrevinin

Tax ID670907

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0302109 VERIFIED: NO