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MYP_043467
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Basic Information
Defensin-6 (Defensin; alpha 6)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
100 amino acids
C469H741N135O153S8
Standard
Sequence
MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSSLRALGSTRAFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL
Physicochemical Analysis
10975.23 Da
5.21
-3.37
-3.79
-0.0337
-0.17
0.57
-0.02
55.34
73.40
0.0800
5960.00
6335.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
4666.26
-55.35
170.0
160.0
361.0
765.0
12.0
107.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0054651 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Alpha-defensin; Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
S. typhimurium
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID8417977;8626737;16421571;15489334;27076903;15616305;25158166;25354318;28026958;30808760;17088326;22722251 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8417977/
RECORD: Rec_0083199 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Alpha-defensin; Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Y. enterocolitica (Gram-negative)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID8417977;8626737;16421571;15489334;27076903;15616305;25158166;25354318;28026958;30808760;17088326;22722251 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8417977/
RECORD: Rec_0087415 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Alpha-defensin; Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
S. thermophilus (Gram-positive)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID8417977;8626737;16421571;15489334;27076903;15616305;25158166;25354318;28026958;30808760;17088326;22722251 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8417977/
RECORD: Rec_0135327 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Alpha-defensin; Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
B. breve (Gram-positive)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID8417977;8626737;16421571;15489334;27076903;15616305;25158166;25354318;28026958;30808760;17088326;22722251 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8417977/
RECORD: Rec_0160626 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Alpha-defensin; Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Escherichia coli (Gram-negative)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID8417977;8626737;16421571;15489334;27076903;15616305;25158166;25354318;28026958;30808760;17088326;22722251 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8417977/
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