Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC527H829N141O169S15

DescriptionStandard

        MKTFSVAVAVAVVLTFICVQQSSAVPVTEQEQELEEPMSMDYPAAAHEEASVDSWKMLYNSRHKRGIKCRFCCGCCTPVSVEFAAGSEDSCSNNHSVLTNCMSQTMCEIILF
    

Molecular Weight12325.04 Da

Isoelectric Point (pI)4.87

Net Charge (pH 7.0)-6.30

Net Charge (pH 7.4) -6.83

Charge Density (pH 7.0) -0.0563

GRAVY Index0.11

Hydrophobic Moment 0.45

Boman Index0.10

Instability Index75.51

Aliphatic Index 71.34

Aromaticity 0.0714

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4947.41

LogP -55.37

H-bond Donors 178.0

H-bond Acceptors 181.0

Rotatable Bonds 404.0

Heavy Atoms 852.0

Ring Count 16.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0108501 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis niloticus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal