Peptide Database

Peptide NameAndroctonus defensin

Function Ontology

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Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC163H249N53O47S6

DescriptionStandard

        GFGCPFDQGACHRHCQSIGRRGGYCAGIIKQTCTCY
    

Molecular Weight3895.44 Da

Isoelectric Point (pI)8.68

Net Charge (pH 7.0)2.87

Net Charge (pH 7.4) 2.48

Charge Density (pH 7.0) 0.0798

GRAVY Index-0.26

Hydrophobic Moment 0.72

Boman Index-0.00

Instability Index83.74

Aliphatic Index 38.06

Aromaticity 0.1111

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1609.83

LogP -20.69

H-bond Donors 63.0

H-bond Acceptors 58.0

Rotatable Bonds 124.0

Heavy Atoms 269.0

Ring Count 7.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425476 VERIFIED: YES

Provenance & Taxonomy

OrganismIxodes scapularis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)