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MYP_043370
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Basic Information
Cecropin A (1-7) + Melittine (2-9) [L4K]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C89H152N22O16
Standard
Sequence
KWKKFKKIGAVLKVL
Physicochemical Analysis
1786.30 Da
10.70
5.75
5.54
0.3836
0.03
0.57
-0.02
-23.33
123.33
0.1333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
642.63
0.03
23.0
22.0
65.0
127.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012672 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC BAA-41
16 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0018697 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
64 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/18852279/ PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0041116 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
0.5-1 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0279113 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 6538P
16 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0295562 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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