Peptide Database

Peptide NameGlia-alpha2 (p61-p71; E66)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC64H89N13O17

DescriptionStandard

        PFPQPELPYPQ
    

Molecular Weight1312.47 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.04

Net Charge (pH 7.4) -1.10

Charge Density (pH 7.0) -0.0945

GRAVY Index-1.20

Hydrophobic Moment 0.16

Boman Index0.06

Instability Index141.16

Aliphatic Index 35.45

Aromaticity 0.1818

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 448.88

LogP -1.67

H-bond Donors 12.0

H-bond Acceptors 16.0

Rotatable Bonds 32.0

Heavy Atoms 94.0

Ring Count 7.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0102160 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E66

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay