Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC438H711N127O147S8

DescriptionStandard

        MKTLVLLSALVLLAFQVQADPIQNTDEETKTEEQPGEEDQAVSVSFGDPEGSSLQEESLRDLVCYCRSRGCKGREHMNGTCRKGHLLYTLCCR
    

Molecular Weight10364.61 Da

Isoelectric Point (pI)4.92

Net Charge (pH 7.0)-5.36

Net Charge (pH 7.4) -5.79

Charge Density (pH 7.0) -0.0576

GRAVY Index-0.46

Hydrophobic Moment 0.59

Boman Index-0.10

Instability Index42.21

Aliphatic Index 77.53

Aromaticity 0.0430

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4454.66

LogP -51.36

H-bond Donors 159.0

H-bond Acceptors 152.0

Rotatable Bonds 353.0

Heavy Atoms 720.0

Ring Count 9.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390866 VERIFIED: NO

Provenance & Taxonomy

OrganismMus spicilegus [Animal]

FamilyDefensin

Tax ID10103

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal