Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC457H736N126O141S7

DescriptionStandard

        MKTIVLLSALVLLAFQVQADPIQKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS
    

Molecular Weight10475.95 Da

Isoelectric Point (pI)5.37

Net Charge (pH 7.0)-2.45

Net Charge (pH 7.4) -2.83

Charge Density (pH 7.0) -0.0263

GRAVY Index-0.12

Hydrophobic Moment 0.63

Boman Index-0.01

Instability Index39.20

Aliphatic Index 86.99

Aromaticity 0.0753

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4345.73

LogP -43.89

H-bond Donors 156.0

H-bond Acceptors 147.0

Rotatable Bonds 358.0

Heavy Atoms 731.0

Ring Count 10.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0366607 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence