Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC165H261N51O54S3

DescriptionStandard

        KCNTATCSMHRLADFLGRSGNNFGAILSPTNVGSNTY
    

Molecular Weight3919.34 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)1.83

Net Charge (pH 7.4) 1.54

Charge Density (pH 7.0) 0.0494

GRAVY Index-0.26

Hydrophobic Moment 0.73

Boman Index0.02

Instability Index30.24

Aliphatic Index 58.11

Aromaticity 0.0811

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1715.45

LogP -25.21

H-bond Donors 62.0

H-bond Acceptors 60.0

Rotatable Bonds 126.0

Heavy Atoms 273.0

Ring Count 5.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232974 VERIFIED: YES

Provenance & Taxonomy

OrganismSaimiri boliviensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)