Peptide Database

Peptide NamePaneth cell-specific alpha-defensin 3

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC449H734N138O148S7

DescriptionStandard

        MKTLALLAALLLLALQVQTQSLEETADQVPAQDQPGAEAQDITISFAGDERSAREASKSLTGTASCTCRRAWVCKWGERHSGNCIDQEGSAYRLCCRR
    

Molecular Weight10657.92 Da

Isoelectric Point (pI)5.76

Net Charge (pH 7.0)-1.45

Net Charge (pH 7.4) -1.83

Charge Density (pH 7.0) -0.0148

GRAVY Index-0.32

Hydrophobic Moment 0.75

Boman Index-0.08

Instability Index46.27

Aliphatic Index 78.88

Aromaticity 0.0408

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4661.05

LogP -57.42

H-bond Donors 170.0

H-bond Acceptors 155.0

Rotatable Bonds 359.0

Heavy Atoms 742.0

Ring Count 9.0

Amide Bonds 106.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0104605 VERIFIED: YES

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic Non-ribosomal