MYP_043117
Vosoritide
Hormonal / Endocrine
▸
Hormone peptide
Standard
39 amino acids
C176H292N56O51S3
Standard
PGQEHPNARKYKGANKKGLSKGCFGLKLDRIGSMSGLGC
4104.74 Da
9.93
6.02
5.87
0.1544
-0.77
0.48
-0.14
14.35
55.13
0.0513
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1739.73
-21.52
63.0
61.0
144.0
286.0
5.0
41.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0187197
VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Growth factor
Structure & Mods
cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone replacement
CHO
The mean half-life following the subcutaneous administration of 15 mcg/kg of vosoritide ranged from 21.0 to 27.9 minutes.[L39229]
RECORD: Rec_0242143
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; synthetic construct [Synthetic]
Natriuretic peptide
9606;32630
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
23-39
Bio-Activity Profile
Bone growth promoter
CNP analogue
Natriuretic peptide receptor B
Clinical/Human: 21.0-27.9 min
RECORD: Rec_0263027
VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Growth factor
Structure & Mods
cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
CHO
The mean half-life following the subcutaneous administration of 15 mcg/kg of vosoritide ranged from 21.0 to 27.9 minutes.[L39229]