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MYP_043113
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Basic Information
Casein beta [51-55], beta-Casomorphin-5
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid receptor ligand
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Stimulation activity
Standard
5 amino acids
C33H43N5O9
Standard
Sequence
YPFVE
Physicochemical Analysis
653.72 Da
4.60
-1.23
-1.44
-0.2466
0.12
0.39
0.38
71.20
58.00
0.4000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
228.46
0.56
7.0
8.0
16.0
47.0
3.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0047488 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Casein-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0138255 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Casomorphin
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Agonist
opioid receptor
PaperBrantl V.. Novel opioid peptides derived from human beta-casein: Human beta-casomorphins. European Journal of Pharmacology, 106, 213-214, 1984.
RECORD: Rec_0159886 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperAmigo L., Mart¨ªnez-Maqueda D., Hern¨¢ndez-Ledesma B.. In silico and in vitro analysis of multifunctionality of animal food-derived peptides. Foods, 9, 991, 2020.
RECORD: Rec_0217904 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
beta-Casein-derived
9606
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cell-proliferative Growth-promoting Beta-cell trophic
Promote beta-cell development
PaperThe protective effects of human milk-derived peptides on the pancreatic islet biology | Singh, A. et al. | DOI: 10.1242/bio.049304 Evidence URLhttps://www.uniprot.org/uniprotkb/P05814/entry
RECORD: Rec_0312269 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Stimulatory
PaperMart¨ªnez-Maqueda D., Miralles B., De Pascual-Teresa S., Rever¨®n I., Mu?oz R., Recio I.. Food-derived peptides stimulate mucin secretion and gene expression in intestinal cells. J. Agric. Food Chem., 60, 8600-8605, 2012.
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