Peptide Database

Peptide NameAlarin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC127H205N43O35

DescriptionStandard

        APAHRSSTFPKWVTKTERGRQPLRS
    

Molecular Weight2894.25 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.88

Net Charge (pH 7.4) 4.64

Charge Density (pH 7.0) 0.1954

GRAVY Index-1.29

Hydrophobic Moment 0.64

Boman Index-0.38

Instability Index97.74

Aliphatic Index 35.20

Aromaticity 0.0800

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1281.23

LogP -15.58

H-bond Donors 47.0

H-bond Acceptors 41.0

Rotatable Bonds 91.0

Heavy Atoms 205.0

Ring Count 7.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0311321 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Familyalarin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Neuropeptide Neuromodulator Growth regulation Development regulation Immunomodulatory

Targetganglionic differentiation in neuroblastic tumor tissue

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

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