Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length552 amino acids

Chemical FormulaC2638H4126N790O808S22

DescriptionStandard

        MGYRSTNYGRGQALHGDRTTTGAICCSTLPNCTEHGRGVIRVGDKTTACPKCGKQGVVADGEPRVNWMGQASAVDGSVVICGCPYGTNRVIAPSGEWLGSGPSPAQVAQEKHLAMLAARRKEQEAEAQRQAEERDRNRVFAKSCLRGEGCNDAGTESEPHTNFAEMAFYQAMPNDAPQHAQAAKRKAIPKPKQRSALYLWWNGHHEEMEYQAAVAAEERAWTARNAIADASELALIGGRTVTPGTWVVRGAALGEIATGGIGAPVAGLLMGMYPGKLNDGEQDFIDRMRAEQMREAPTRVRFTWESDASGNPTPRGWHTPPGKDSVRVRTMEWDSRRQAYTFTTEEDPGITLIWTPDRTGESKPWDTGNHNPVRISNPVVVDPLPEDTGVGATISPTPEEKTFADYILILPVGGVPPIYVYIRHNPGQVTGKGQKISGIWLSDANTGNGSPIPSQIADRLRGQTFTDFDQFRKAFWLEVSRDPILLEQFISNNRASMRKGNAPYTRTPDSVGKRERYEIHHIQPISQGGKVYDVDNMGITTPKHHIKIHKGE
    

Molecular Weight60541.22 Da

Isoelectric Point (pI)7.64

Net Charge (pH 7.0)1.82

Net Charge (pH 7.4) 0.57

Charge Density (pH 7.0) 0.0033

GRAVY Index-0.63

Hydrophobic Moment 0.74

Boman Index-0.07

Instability Index35.44

Aliphatic Index 63.68

Aromaticity 0.0707

Extinction Coeff. Reduced 92360.00

Extinction Coeff. Oxidized 92860.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066680 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacter sp. HN503E2II [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)