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MYP_042980
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Basic Information
Temporin-SHa G10Y analog
Anticancer
Antimicrobial
Standard
13 amino acids
C74H114N14O16S
Standard
Sequence
FLSGIVGMLYKLF
Physicochemical Analysis
1487.85 Da
8.59
0.76
0.55
0.0583
1.60
0.43
0.63
-16.89
142.31
0.2308
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
479.00
0.63
17.0
18.0
48.0
105.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017252 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is similar (92.31%) to temporin-SHa L: 23%, F=G=K: 15%. Chemical modification: Y10 is a D-amino acid; C-terminal amidation
Bio-Activity Profile
Antimicrobial Anticancer
Enterococcus faecalis DSM 2570
12.5 μM
MIC
PaperSynthesis of Second-Generation Analogs of Temporin-SHa Peptide Having Broad-Spectrum Antibacterial and Anticancer Effects
RECORD: Rec_0038502 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is similar (92.31%) to temporin-SHa L: 23%, F=G=K: 15%. Chemical modification: Y10 is a D-amino acid; C-terminal amidation
Bio-Activity Profile
Antimicrobial Anticancer
normal lung fibroblast IMR-90
38.2 μM
IC50
PaperSynthesis of Second-Generation Analogs of Temporin-SHa Peptide Having Broad-Spectrum Antibacterial and Anticancer Effects
RECORD: Rec_0067930 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is similar (92.31%) to temporin-SHa L: 23%, F=G=K: 15%. Chemical modification: Y10 is a D-amino acid; C-terminal amidation
Bio-Activity Profile
Antimicrobial Anticancer
Bacillus subtilis ATCC 6633
6.25 μM
MIC
PaperSynthesis of Second-Generation Analogs of Temporin-SHa Peptide Having Broad-Spectrum Antibacterial and Anticancer Effects
RECORD: Rec_0091852 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is similar (92.31%) to temporin-SHa L: 23%, F=G=K: 15%. Chemical modification: Y10 is a D-amino acid; C-terminal amidation
Bio-Activity Profile
Antimicrobial Anticancer
K.pneumonia DSM 26371
>100 μM
MIC
PaperSynthesis of Second-Generation Analogs of Temporin-SHa Peptide Having Broad-Spectrum Antibacterial and Anticancer Effects
RECORD: Rec_0095567 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is similar (92.31%) to temporin-SHa L: 23%, F=G=K: 15%. Chemical modification: Y10 is a D-amino acid; C-terminal amidation
Bio-Activity Profile
Antimicrobial Anticancer
Pseudomonas aeruginosa ATCC 9027
>100 μM
MIC
PaperSynthesis of Second-Generation Analogs of Temporin-SHa Peptide Having Broad-Spectrum Antibacterial and Anticancer Effects
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