Peptide Database

Peptide NameGly8-Glu22-GLP-1-CEx-Linker-IgG1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC153H230N40O49

DescriptionStandard

        HGEGTFTSDVSSYLEEQAAKEFIAWLVKGRG
    

Molecular Weight3413.70 Da

Isoelectric Point (pI)4.96

Net Charge (pH 7.0)-2.14

Net Charge (pH 7.4) -2.41

Charge Density (pH 7.0) -0.0691

GRAVY Index-0.41

Hydrophobic Moment 0.48

Boman Index0.05

Instability Index25.66

Aliphatic Index 66.13

Aromaticity 0.1290

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1445.70

LogP -14.44

H-bond Donors 51.0

H-bond Acceptors 48.0

Rotatable Bonds 113.0

Heavy Atoms 242.0

Ring Count 6.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0379066 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGLP-1

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermLinking IgG1 using CEx-Linker (SSGAPPPS-GGGGSGGGGSGGGGS)

Bio-Activity Profile

Function

Insulinotropic

MethodRadioimmunoassay

Half-LifeDog plasma (Subcutaneous), in vivo; 136800 s