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MYP_042938
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Basic Information
Bovine myeloid antimicrobial peptide-18 (BMAP-18)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C113H188N34O20
Standard
Sequence
GRFKRFRKKFKKLFKKLS
Physicochemical Analysis
2342.92 Da
12.00
9.75
9.54
0.5418
-1.29
0.82
-0.61
-6.93
43.33
0.2222
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
946.09
-4.98
36.0
30.0
88.0
167.0
4.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0172726 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus ATCC 25923
2 μM
MIC
PMID8910461 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8910461/
RECORD: Rec_0178044 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPatent US 10723764 B2 Evidence URLhttps://patents.google.com/patent/US10723764B2/en PatentUS 10723764 B2
RECORD: Rec_0183103 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Antiparasitic Anti-inflammatory
Staphylococcus epidermidis ATCC 12228
1-4 μM
MIC
PaperBiological characterization of two novel cathelicidin-derived peptides and identification of structural requirements for their antimicrobial and cell lytic activities PMID34642879 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34642879/
RECORD: Rec_0217049 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Cathelicidin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ML35
4 μM
MIC
PMID8910461 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8910461/
RECORD: Rec_0219296 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
400 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/21497177/ PMID21497177 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21497177/
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