‹ ›
MYP_042891
← PREVIOUS NEXT → BACK
Basic Information
Cupiennin 1a
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
35 amino acids
C176H289N47O44S
Standard
Sequence
GFGALFKFLAKKVAKTVAKQAAKQGAKYVVNKQME
Physicochemical Analysis
3799.53 Da
10.30
6.76
6.54
0.1931
-0.13
0.69
0.02
25.17
75.43
0.1143
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1511.00
-11.99
51.0
52.0
135.0
268.0
4.0
38.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0036618 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Cationic peptide 04 (cupiennin); 01 subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Hemolytic Insecticidal Synergistic peptide
P. denitrificans (Gram-negative)
PMID11792701;10669026;15914655;17313650;17319697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11792701/
RECORD: Rec_0048495 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Cupiennin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
0.31 - 0.63 μM
MIC
PMID11792701 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11792701/
RECORD: Rec_0063375 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Cationic peptide 04 (cupiennin); 01 subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Hemolytic Insecticidal Synergistic peptide
P. putida (Gram-negative)
PMID11792701;10669026;15914655;17313650;17319697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11792701/
RECORD: Rec_0063888 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Cationic peptide 04 (cupiennin); 01 subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Hemolytic Insecticidal Synergistic peptide
Pseudomonas aeruginosa (Gram-negative)
PMID11792701;10669026;15914655;17313650;17319697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11792701/
RECORD: Rec_0109595 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Cupiennin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
0.31 - 0.63 μM
MIC
PMID11792701 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11792701/
FIRST PREV 1 2 3 4 ... 8 NEXT LAST
Showing 5 records on this page · Page 2 of 8