Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC416H690N114O121S11

DescriptionStandard

        MRLLLMALPLLALLPQVIPDYSAEKRCLNRLGHCKRKCKAGEMVMETCKYFQVCCVLDDNDYKQKASITRTMEKTSTIEYNLS
    

Molecular Weight9577.33 Da

Isoelectric Point (pI)8.80

Net Charge (pH 7.0)3.53

Net Charge (pH 7.4) 3.15

Charge Density (pH 7.0) 0.0426

GRAVY Index-0.18

Hydrophobic Moment 0.60

Boman Index-0.07

Instability Index30.85

Aliphatic Index 90.48

Aromaticity 0.0602

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3826.72

LogP -33.44

H-bond Donors 139.0

H-bond Acceptors 137.0

Rotatable Bonds 328.0

Heavy Atoms 662.0

Ring Count 9.0

Amide Bonds 88.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006549 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10116

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

RECORD: Rec_0280989 VERIFIED: YES