Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length387 amino acids

Chemical FormulaC1915H3057N513O529S19

DescriptionStandard

        MAREPGKALMRATLVVLATLGTAVIATTNPGVVARITQKGLDYACQQGMVVLRKELEKITIPTFSGTFKIKHLGKGHYSFYSMAIRGFQLPSSQMKLVPSEGLNLAIRNANVMISGKWKARKNFIKISGNFDLSVEGVSISAVLKPGFDPTSGRCTVTCSSCSNHIDSVRVHVSGSRLGWLIKLFHKKIESSLRKMMNNKICQVVTNSVSSKLQGYLKTLPVKTRIDHVAGIDYSLVAPPTATADNLDGQLKGEFFRCGQHSPPPFAPPPLAFPNDHDRMLYLGISDYFFNTAGLVYQQAGVLNLTVTDDMIPKKSKFRLTTDFFGILIPQVAQMFPNMKVQLVFWASSPPHLTMNPAGLVLTPTLDAQAFAVLPDSSLAPLFVLRL
    

Molecular Weight42340.11 Da

Isoelectric Point (pI)9.78

Net Charge (pH 7.0)19.23

Net Charge (pH 7.4) 18.40

Charge Density (pH 7.0) 0.0497

GRAVY Index0.09

Hydrophobic Moment 0.71

Boman Index0.12

Instability Index32.96

Aliphatic Index 93.95

Aromaticity 0.0827

Extinction Coeff. Reduced 28420.00

Extinction Coeff. Oxidized 28795.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0005413 VERIFIED: NO

Provenance & Taxonomy

OrganismCrocuta crocuta [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria