MYP_042854
Basic Information
RTD-2 (RTD 2, rhesus theta-defensin 2)
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Antiviral
Antiviral Anti-HIV Anti-HIV-1
Antiviral Antiviral mechanism Viral entry inhibition
Standard
18 amino acids
C80H150N36O19S6
Standard
Sequence
GVCRCLCRRGVCRCLCRR
Physicochemical Analysis
2112.67 Da
9.69
5.70
5.41
0.3167
0.18
0.61
-0.46
89.77
75.56
0.0000
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
929.42
-11.53
43.0
31.0
71.0
141.0
0.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0272812 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral Anti-Gram-positive Anti-Gram-negative
RECORD: Rec_0311300 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
drug resistant Candida albicans clinical isolates
6.2-25 μg/mL
MIC
RECORD: Rec_0365185 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 55.6%, C 44.4% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
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