Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC424H679N119O127S15

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAVPFTGVQELEEAGSNDAPVAAYQEMSMESRMMPDHIRQKRQSQLSMCRYCCNCCKANKGCGFCCRF
    

Molecular Weight9956.62 Da

Isoelectric Point (pI)7.48

Net Charge (pH 7.0)0.51

Net Charge (pH 7.4) 0.09

Charge Density (pH 7.0) 0.0057

GRAVY Index0.16

Hydrophobic Moment 0.57

Boman Index0.06

Instability Index64.11

Aliphatic Index 69.44

Aromaticity 0.0778

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3954.99

LogP -42.27

H-bond Donors 145.0

H-bond Acceptors 144.0

Rotatable Bonds 332.0

Heavy Atoms 685.0

Ring Count 11.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0278362 VERIFIED: NO

Provenance & Taxonomy

OrganismCentropristis striata [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal