Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length207 amino acids

Chemical FormulaC1054H1616N238O315S10

DescriptionStandard

        CIHKIILVLVIFCVLSTTLTAVMQIDDLAEVDYSLSGLPAVFQPFIDLDLKGIVFPAGNHTDYPYVASSFTIPDHSDSMLYLAFSEYFFQTSSFAYYTTGAFNMTIAEETCSYFHINTEIFSSIIPEVAKYSVTPYPVMLKLMSTEIPTISLQQDSFTVEIQGSVEVLTILPDSTPQSLFTLNIAANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight22982.16 Da

Isoelectric Point (pI)4.24

Net Charge (pH 7.0)-13.91

Net Charge (pH 7.4) -14.42

Charge Density (pH 7.0) -0.0672

GRAVY Index0.45

Hydrophobic Moment 0.55

Boman Index0.28

Instability Index43.61

Aliphatic Index 104.54

Aromaticity 0.1208

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15150.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0376378 VERIFIED: NO

Provenance & Taxonomy

OrganismNesospiza acunhae [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

Target-